15129180607

15129180607

Caryophyllene Oxide
admin 2024-01-05
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Product Description

Appearance: Pale yellow to white crystal powder

Odor: Sweet fruity aroma

Purity: >=95%

Boiling point: 138-141 ° C | Condition: Press: 10 Torr

Density: 0.9488 g/cm3 | Condition: Temp: 20 ° C

Melting point: 55-62°C

Storage conditionThis product is stored in a cool and ventilated place. Avoid miscellaneous air pollution


What is Caryophyllene Oxide? 

Caryophyllene oxide is a sesquiterpene that results from the oxidation of β-caryophyllene, which can occur during the harvest's cure. It is also considered non-toxic, and non-sensitizing, and has been indicated as an anticoagulant with platelets.

Caryophyllene oxide is present in plants' profiles like eucalyptus, lemon balm, oregano, wormwood, rosemary, guava, black pepper, and clove. It has been used in cosmetics, drugs, food preservatives, and for training drug-sniffing dogs by law enforcement.  

This terpene interacts with the endocannabinoid system by binding directly with CB2 receptors. Like other terpenes, its benefits include anticancer, anti-inflammatory, analgesic, and anti-bacterial properties. It has been compared to ciclopirox olamine and sulconazole as an antifungal, mainly used in toenail fungus treatment and other skin and nail fungi.

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Product use:


1. It is used for food, milk and bread aroma (to increase the flavor) to improve the taste and make the aroma lasting.

2. It is used for shampoo, facial mask, cream, body wash, perfume, soap, daily cosmetics, and lasting fragrance.

3. Used for electronic cigarettes, tobacco, blending, adding flavor and improving aroma.

4. Professional perfumers can use the formula to improve the fragrance and make it attractive.

Application


The Application of Caryophyllene oxide:

1. Used in the manufacturing of lavender fragrances;
2. Used in all food and beverage flavors;
3. Used in the pharmaceutical industry, such as used as an effective antifungal, anesthetic, antioxidant, and anticoagulant with platelets.

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The Function of Caryophyllene oxide:

Caryophyllene Oxide has been identified to be beneficial as:
1. Anticoagulant
A recent study suggests that isolated Caryophyllene oxide showed significant anti-platelet aggregation activity, indicating it could potentially prevent coagulation of the blood (Yang, Millet-Clerc, Chaumont, & Michel, 1999).
2. Anticancer
Like many other terpenes, Caryophyllene can help potentiate anti-cancer drug efficacy. For example, it can enhance the chemotherapy drug doxorubicin in the treatment of intestinal cancer cells.   Besides, combined with doxorubicin and paclitaxel shows anticancer activities in human leukemia, multiple myeloma, and human prostate cancer cell lines.   In general, Caryophyllene has "equally strong (or even stronger) anticancer activity than [β-caryophyllene]." Further research is needed to determine if it prevents cell proliferation and induces apoptosis.   ( Sain, S., 2014)
3. Antifungal
Caryophyllene Oxide is also known for its antifungal properties.   When tested on nail and skin fungi, the terpene's antifungal activity is comparable to fungal treatment drugs, such as ciclopirox olamine and sulconazole (yang, Millet-Clerc, Chaumont, & Michel, 1999).
4. Anti-Inflammatory
Another benefit of Caryophyllene Oxide is its analgesic and anti-inflammatory properties. Caryophyllene oxide combined with unsaponified petroleum ether extract showed significant central and peripheral analgesic, along with anti-inflammatory activity. These activities of caryophyllene oxide were comparable with the standard drug used in the respective experiments (Javed, Azimullah, Haque, & Ojha, 2016).


Packing and shipping


Packaging: 1 kg aluminum foil bag; 10 kg carton packaging; 25 kg cardboard drum packaging; we also can customize the package according to customers' demands.

Shipping: Shipping by express, air, Sea, and some special line to most Countries.

Normally for small quantities, we will ship them by DHL, FedEx, UPS, special line, and so on, for big quantities By Air, Sea, and some special line to most Countries.

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FAQ

Q1: Could you provide free samples for testing?
A1: Yes, we can provide free testing, and shipping costs are paid by our customers.

Q2: Which payment terms do you accept?
A2: Alibaba online order, PayPal, West Union, T/T, etc.

Q3: What about the MOQ?
A3: The MOQ of each flavor is 125ml, but the first weight of the shipping fee is 1L, we recommend you buy 1L or 125ml*8, which will be more economical.

Q4: What's the delivery time?
A4: The goods will be sent out about 3 days after receiving the payment, the delivery time is about 6-15 days.

Q5: What about the Shipping method?
A5: Door to Door by FedEx, TNT, UPS, DHL, Dedicated Line, etc.

Q6: Which country can you ship to?
A6: We can ship to almost every country all over the world, and we have a stable shipping method. If you have a forwarder agent in China, we can also send the goods to your shipping agent freely.

Q7: How to order?
Leave us a message, we'll send you our product list price lists for your reference.